Metal-organic frameworks are highly efficient, customizable chemical catalysts that recently earned pioneer Omar M. Yaghi the 2025 Nobel Prize in Chemistry. Yaghi has since relocated his research to Tsinghua University in China, citing slashed US research funding, restricted international collaborations, and a stronger push for AI-driven science. His departure underscores growing concerns about the defunding of American research institutions and the resulting brain drain of top scientific talent.